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Among these cells, it is now well admitted that microglia appears to be a major cellular contributor of post-ischemic inflammation [4].
The pathogenesis of ischemic stroke is a complex sequence of events including inflammatory reaction, for which the microglia appears to be a major cellular contributor.
As the ability to form memories is thought to be encoded by modifications in synaptic strength, LTP is considered to be a major cellular mechanism underlying learning and memory.
Myosin IIA appears to be a major cellular target of mts1 [45], the small calcium-binding protein metastasin-1, and co-localizes with mts1 to the leading edge of migrating cancer cells [46]; mts1 influences both the assembly behavior of myosin IIA and its phosphorylation [47], [48].
Surprisingly, fibroblasts appeared to be a major cellular source of TLR9 expression in IPF biopsies from this group of progressors.
This suggests that circulating monocytes may be a major cellular source of TLR2 expression in patients with AMI.
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Ribosome biosynthesis, which takes place in nucleoli, is a major cellular undertaking.
SAM is probably second only to ATP in the variety of reactions for which it serves as a cofactor, and is also a precursor of glutathione, which is a major cellular anti-oxidant (Caro and Cederbaum 2004).
Activation of p53 is a major cellular response to DNA damage [20] [20].
gclc catalyzes a step in glutathione biosynthesis, which is a major cellular antioxidant, and peroxiredoxin-1 reduces peroxides.
Catalase is a major cellular antioxidant enzyme normally expressed in the peroxisomes (abbreviated as PCAT in this manuscript).
More suggestions(15)
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Justyna Jupowicz-Kozak
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