Sentence examples for be a main effector from inspiring English sources

Interestingly, a previous study indicated that high glucose was sufficient by itself to induce an autocrine production of TGF- β1 in cultured human peritoneal MCs and could therefore be a main effector of the activation of the Smad-dependent pathway in our culture model that is using a BMe.

Obesity is a main effector of BP in children [ 14, 15, 25, 30- 33].

Furthermore, we found that induction of Gadd45 α is a main effector event in apoptosis triggering by Shigella.

Angiotensin II is a main effector peptide in the renin-angiotensin system and plays a very important role in controlling renal homeostasis as a vasoconstrictor.

This cascade is a main effector pathway of ERBB receptors, and altered in a high percentage of cancers usually be mutation of Ras or BRAFgenes.

CDKN1A, downregulated by M1775R, is a main effector of cell cycle arrest in response to DNA damage and a promoter of apoptosis [ 28].

Angiotensin II (Ang II) is a main effector peptide in the renin angiotensin system and participates in the regulation of vascular tone.

Angiotensin II (Ang II) is a main effector of the RAS acting on homeostasis and cardiovascular function, through the type 1 (and) and type 2 (AT2) receptors [ 10].

PI3K activation and subsequent PIP3 production induce activation of multiple signalling molecules, including Akt, which is a main effector of PI3K.

AIF is a main effector in the caspase-independent necroptotic process induced by the treatment of MEFs with high doses of the nitrosourea MNNG.

The rationale was that angiotensin II is a main effector peptide in the renin-angiotensin system and plays a very important role in controlling renal homeostasis as a vasoconstrictor.