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Activin A is known to be a local regulator of early follicle development [27], [28], [29].
Although CNP is known to be a local regulator of vascular tone and growth, CNP can be detected in human circulation [ 119].
31 It has been suggested that the production of TNF-α by adipose tissue could be a local regulator of fat cell size and that the overproduction of TNF-α in adipocytes of obese individuals could be a homeostatic mechanism that is designed to limit further increases in adipocyte size.
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Despite its global regulatory role, CodY, as explained previously, is a local regulator for this pathway.
However, CodY can be considered as a local regulator for BCAA synthesis.
Given that NPY is expressed in osteoblasts, these data further support the concept that NPY could be a direct local regulator of osteoblast function, in addition to effects mediated via the hypothalamus, and highlights the fact that NPY may act via neuronal as well as autocrine mechanisms to regulate bone homeostasis.
In the primary control layer, each generation unit is equipped with a local regulator for voltage and frequency stability acting on the corresponding voltage-source converter.
The greater effect of IGF-I on bone mass, architecture, and mechanical properties than TGF-β2 may be explained by IGF-I having both systemic and local roles in bone metabolism and TGF-β being a more local regulator of bone remodeling.
Serotonin (5-HT) is a critical local regulator of epithelial homeostasis in the breast and other organs.
However, by considering the number of FFs in which a TF is a master or local regulator, it is possible to infer its role in the entire TFN.
Like other European banks, Société Générale is being required by local regulators to hold more capital in reserve.
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