Sentence examples for be a linear epitope from inspiring English sources

Our results suggested that this epitope should be a linear epitope of rhTNF-α.

The WB result suggested that the epitope recognized by AVFluIgG01 may be a linear epitope, while the epitope recognized by AVFluIgG03 may be a conformational epitope.

One reason for the disparity in mimotope urease B sequences might be that the epitopes that are recognised by the generated mAbs could be a linear or conformational epitope that consists of a discontinuous amino acid sequence.

Previous studies suggested that the COOH-terminal sequence YLGTRR appears to be a major linear epitope of HCCR [ 18].

The mutation A337V is included to produce a linear epitope for mAb 3A6, as in Mendez et al. (2000).

For example, in Figure 8(a), "YPGHVSGHRMAWDMM" is a linear B-cell epitope which mainly forms a helix structure (blue), whereas "RLWHYPCTINYTIFKI" is a non B-cell epitope that possesses an alpha structure (red) as well as a helix structure (blue).

A linear epitope is composed of a single continuous sequence segment.

We show that due to ensemble properties of unbiased mixtures, the position of amino acids in a linear epitope is no longer determinative for binding prediction.

Therefore, the most likely explanations for a loss of reactivity in immunohistochemistry is that the linear epitope has been cleaved and is no longer recognized by the antibody, or that the protein has been degraded to such an extent that proteolytic fragments containing the epitope no longer exist.

Specifically, recognition of an early detection serological epitope 'E2EP3', which is a dominant linear B-cell epitope in CHIKV-infected patients and animal models (Kam et al, 2012a, b; Lum et al, 2013), was significantly diminished (Fig E– G).

It has been shown that linear epitopes, as well as mimotopes that mimic discontinuous epitopes of an antigen, can be identified by the screening of phage libraries with monoclonal or polyclonal antibodies [ 15, 16].