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"What is sleep?" might be a less profitable question than "What is awake?" Mignot had done something very unusual: he had discovered the genetic cause of a condition, helped to reframe thinking about a fundamental human behavior, and revealed clear pharmaceutical opportunities.
Pharmaceutical laboratories invest very little money in researching and finding treatments for children, perhaps because they consider it to be a less profitable endeavor.
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The combination meant that it was a less profitable quarter than the same period a year ago.
(If you are a less profitable customer or are looking for basic information like store hours and directions, though, you may find yourself referred to what are known as self-service channels like the Internet or additional voice menus).
Because dial-up access is a less profitable business for AOL than e-commerce and advertising.
Those figures may recover as the market lifts, but Moody's and other ratings agencies are still cautioning that Wall Street may be stuck with a less profitable, more constrained business model for the foreseeable future.
"Mack will be criticized for that because it will be a lot less profitable perhaps, but there is a lot less downside".
Almost all are still reporting steep falls in revenue from investment banking, and commercial banking is proving to be a lot less profitable than it was.A casual observer could be forgiven for thinking it was a decent quarter, with many banks posting higher year-on-year operating profits.
"We are doing some corporate work, but we turn down a lot of work if it's time that we could be spending on a race that we care about, where it's a lot less profitable because there just isn't that kind of money in politics," said Kriegel, 32.
*** The funny thing about upgrading my service in this fashion is that I've likely become a less profitable customer for Comcast than when I was just a pure broadband subscriber.
Competitors said they were not eager to follow Mr. Weill into insurance and banking, saying, as he conceded yesterday, that insurance was a much less profitable business.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com