Sentence examples for be a key pathological from inspiring English sources

This protective effect may occur because these polymorphisms reduce the vaso-occlusive effects of rosetting [12], thought to be a key pathological process in severe malaria [13].

Similarly, cytoplasmic inclusions of ALS8 mutant VAPB are likely to be a key pathological feature of ALS8.

In the present study, we show that Ercc1 Δ /− motor neurons do not develop TDP43 pathology which is a key pathological feature in the majority of ALS patients [ 46], a minority of which have mutations in the TDP43 gene, while the majority being caused by mechanisms that remain to be defined [ 31, 47].

The misfolding of proteins to form amyloid is a key pathological feature of several progressive, and currently incurable, diseases.

Microcirculatory dysfunction is a key pathological mechanism involved in septic shock patients and could, also, be exacerbated by acute changes in alveolar ventilation.

Lewy bodies are a key pathological feature of PD.

The accumulation of protease resistant conformers of the prion protein (PrPres) is a key pathological feature of prion diseases.

Neuroinflammation is a key pathological occurrence of secondary injury contributing to brain damage after blast injury.

Amyloid deposition is a key pathological event in Alzheimer's disease.

It is well known that ox-LDL-induced endothelial cell injury is a key pathological process in atherosclerosis.

Our findings provide the first direct evidence that alpha-synuclein self-interaction is a key pathological marker in diseased brain.