Sentence examples for be a key pathogenic from inspiring English sources

Brain endothelial dysfunction indicated by higher levels of sVCAM-1 may be a key pathogenic mechanism.

Angiogenesis is known to be a key pathogenic feature of psoriasis.

The retention of modified low-density lipoproteins is felt to be a key pathogenic event and possibly an absolute requirement for lesion development and progression [ 14, 15].

Oxidant/antioxidant imbalance is believed to be a key pathogenic factor in chronic inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease (COPD) (31).

Failure to achieve programmed cell death and to clear apoptotic cell fragments could be a key pathogenic factor in the development of autoimmunity.

IFN-γ increases the sensitivity of Fas-mediated apoptosis of keratinocytes, which is considered to be a key pathogenic event in eczematous dermatitis [ 5].

We propose that reduction of maternal blood flow in the placenta is a key pathogenic factor in murine pregnancy malaria and we hypothesize that exacerbated innate inflammatory responses to Plasmodium infected red blood cells trigger severe placenta pathology.

TNF-α is a key pathogenic factor in inflammatory arthritis.

These results are clinically important, as oxidative stress is a key pathogenic factor in diabetes.

Insulin resistance triggered by excess fat is a key pathogenic factor that promotes type 2 diabetes.

Excessive neutrophil infiltration to the lung is a key pathogenic feature for disease progression in individuals with CF and COPD.