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These analyses support a primary role for CTCF in the global organization of chromatin architecture and suggest that CTCF may be a heritable component of an epigenetic system regulating the interplay between DNA methylation, higher-order chromatin structure, and lineage-specific gene expression.
Thus, the results of Experiment 2 suggest that specific face recognition difficulties may be a heritable component of the BAP that is distinct from general ability.
Recent evidence indicates that CTCF is involved in the global organization of chromatin, and "may be a heritable component of an epigenetic system regulating the interplay between DNA methylation, higher-order chromatin structure, and lineage-specific gene expression" [3].
Therefore, although there appears to be a heritable component to MPD, the contributing genetic variants have not been fully elucidated.
It is possible to hypothesize that there may be a heritable component to hand OA that contributes to the concept of osteophyte load as well as the site of affected joints.
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There is a heritable component in IBS, and genetic research is a valuable tool for the identification of causative pathways, which will provide important insight into the pathophysiology.
These findings provide evidence that there is a heritable component to autism.
It has long been recognized that there is a heritable component for the development of atopic dermatitis (AD) (Barnes, 2010).
We used genome scans of 331 polymorphic AFLP markers to test whether there was a heritable component to the observed morphological diversification.
This supports the hypothesis that there is a heritable component of the disease, and represents an endophenotype of juvenile myoclonic epilepsy, defined as an intermediate phenotype that appears to be more frequently present in non-affected family members than in the general population.
However, there is also a heritable component to this choice, where the actual threshold levels of adiposity and/or growth rates that need to be reached in order for early sexual maturation to commence, are partially genetically determined (for review see Fleming 1996).
More suggestions(15)
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