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In the same context of rewiring (but not in a combinatorial manner), Haseltine & Arnold (2008) attempted to rewire the quorum-sensing module from Vibrio fischeri in an E. coli host and showed that with small changes in network connectivity, the response to the input can be a graded, threshold or bistable gene expression.
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It's A-grade.
He's a grade thirteener.
It's a grade school!
There will also be a lower threshold.
The distinction between G1 and G2 NENs is based on a very subtle difference in the proliferative rate, which may not be optimal grading threshold and hence accountable for the discrepancy in grading and prognostic value.
Vibration detection threshold will be measured with a graded tuning fork (Rydel-Seiffer, 64 Hz) placed over three bony prominences (ulnar styloid, patella and medial malleolus).
Sixth grade is a threshold year for many children — it's the first year of middle school, which brings heavier academic and social pressures, and it's when many children who fall behind drop out of school emotionally, even if they don't physically stop showing up until high school.
He believes that deal may have opened the eyes of other large companies that, yes they can handle enterprise-grade security and he said that was a significant threshold to cross.
"There's a credibility threshold".
In software, $100 million is a high threshold.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com