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In neoadjuvant CRT patients, high levels of Bax expression and low levels of VEGF and MMP-9 expression on preoperative biopsies indicate that the patient will potentially be a good pathological responder.
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Past research has shown that variations in electrical impedance among tissues can be a good marker of pathological changes in human and animal subjects [ 2– 11].
In oesophageal cancer, Kim et al. identified that a complete metabolic response on [F]FDG-PET was a good predictor of pathological response and survival after chemoradiotherapy.
There is a good agreement between pathological findings and changes in kinetic parameters obtained with breast-MRI in high spatial and low temporal resolution when measured-AIF is used.
The blood features are a good index of physiological and pathological status in man and animals and the parameters usually measured are haemoglobin, total red blood cells (RBC), leukocytes (WBC), MCV, MCH, MCHC, neutrophils, lymphocytes, eosinophils and number of platelets [ 23].
In patients with a good pathological response, the post-treatment median CD105-positive count was lower than those with no pathological response, but this did not achieve significance.
Several retrospective studies have demonstrated that in patients with a good pathological response to NAC, adding bevacizumab to the cytotoxic drugs was associated with a better outcome [20 22].
On the other hand, other approaches such as [ 11, 23] have already demonstrated that MS is a good source of information to detect pathological voices or to perform an automatic pathology classification.
The test model replaces the clinical pathological test results from the pragmatic model with a measure of comorbidity (modified Charlson comorbidity score) to determine whether these clinical pathological test results are a good alternative for measuring case-mix.
All BI-RADS 4 and BI-RADS 5 lesions, and some BI-RADS 3 ones, should be percutaneously punctured, and in cases with benign results, surgery can be avoided if there is a good radiological pathological correlation and no borderline result is obtained.
The presence of tumour infiltrating lymphocytes (TIL) within rectal tumour tissues is considered to be an independent pathological marker of good prognosis (Harrison et al, 1994).
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