If the study is designed to address the research question and conducted appropriately, the analysis is generally straightforward: there should be sufficient statistical power to address the study hypotheses or specific aims, and the analyses will fall directly from the hypotheses or aims.
While measurement of D V/ K) (and D V) (Table 2) is generally straightforward (if a suitable deuterated substrate is available), estimating D k for a reaction may be more complex because of "masking" that results from "commitment to catalysis" and related factors.
This would be a straightforward question with a straightforward answer.
Returning signed prescriptions to patients was generally straightforward: they were sent by post, picked up in person, or collected by a designated pharmacy.
Alignments for the nuclear introns were generally straightforward, but were algorithmically aligned with ClustalX 1.8 [ 42] and MUSCLE [ 43] and adjusted by hand.
Although the application of proximity models is generally straightforward, this method is limited in the assumption that subjects within a given distance of an exposure source are equally exposed.
Although a few rearrangements were observed elsewhere in the genome, these are generally straightforward events such as deletions or tandem duplications and do not intersect with the regions of massive disruption shown in Figure 2.
Historically, the treatment of hyponatraemia due to SIADH has been challenging, whilst the treatment of hypovolaemic hyponatraemia is generally straightforward, but novel treatments such as vasopressin-2 antagonists may be important in enabling treatment in patients who, prior to correction of their hyponatraemia, would not have had a performance status sufficient to permit chemotherapy.
