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Thus, triggering of apoptosis appears to be a general cellular response to elevated mOGT expression.
AMPK mediated Nedd4-2 acouldtherebyuld therebe be speculated to be a general cellular mechanism to remove ion channels from the membrane during cellular stress.
Therefore, the translocation (or partitioning) of RING E3 ligases may be a general cellular mechanism through which plants adapt to the environment via post-translational modifications.
Our findings indicate that the biochemical changes caused by the pathogenic A3243G mutation are not dependent on tissue type and therefore, it seems to be a general cellular compensatory mechanism.
It is intriguing to speculate that lysine acetylation of substrate binding sites may be a general cellular mechanism to control metabolic enzyme activity in a manner analogous to phosphorylation-dependent regulation of protein kinases and signal transducers.
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But if production of ROS and caspase activation in response to transcriptional events is a general cellular response to HDAC inhibition why the preferential sensitivity of tumor cells?
Whether the detected changes in expression are a general cellular response of fish gill to low calcium and/or are more specifically related to the Ca2+ uptake pathway to maintain body calcium balance remains to be determined.
We find that focal adhesions segregate TβRI from TβRII in both epithelial and mesenchymal cell lineages, opening the possibility that this is a general cellular mechanism for the control of TGFβ signaling.
Self-organization might be a general principle in cellular organization and an elegant, efficient way to optimally organize cellular structures [ 53]. 7) Self-organization occurs when a real system evolves toward a higher differentiation from its initial state (or pre- system phase) [ 51].
Therefore, AMPK could be a general activator of cellular senescence.
Collectively, induction of HDAC1 acetylation may be a general event for cellular stress response.
More suggestions(15)
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com