These data demonstrate that the sulfonylurea resistance cassette from M. oryzae is a functional dominant selection marker in Z. tritici.
Unlike gene duplication, gene loss is not an unspecific mechanism but is rather influenced by a functional selection.
There are issues, and the software will continue to get better and offer more features, but this is a functional platform with a wide selection of available games and experiences.
Again, various subsets of amino acids including putative primitive amino acids should be tested for functional selection depending on the target function, because some putative new amino acids may be essential for some function.
Selection of the binding sequence in promoter regions by AhR should be related to functional selection of AhR toxicity.
We extracted as high-confidence target sites the top 1000 sites in the order of their posterior probability of being under functional selection.
One of the major shortcomings of previous work was the difficulty of discerning which groups of sites were under functional selection given statistical procedures that were designed under the assumption of site-independence.
Previously, it has been reported that such reduced alphabets are effective for functional selection from randomized libraries [23], [24].
A recent study in Drosophila showed that the high robustness of pre-miRNAs secondary structure is likely to be a consequence of selection for functional structures [ 26].
This suggests that, while there is flexibility or relaxed selection for the tethering machinery, there is more restrictive functional selection and resulting evolutionary constraints on the SM proteins.
