Sentence examples for be a frequent abnormality from inspiring English sources

This rate has almost tripled the prevalence found in the fertile control group, which appears to be a frequent abnormality in idiopathic infertile men, playing a significant role in causing infertility.

In this study, loss of p53 was shown to be a frequent abnormality in premalignant tissue.

Conclusion LVDD is a frequent abnormality in the ICU setting, associated with an important morbi-mortality.

Fan, CS et al indicated that c-Myc overexpression is a frequent genetic abnormality in NPC.

Elevated expression of c-Myc is a frequent genetic abnormality seen in this malignancy.

Deletion or inactivation of genes within this region is a frequent cytogenetic abnormality in other malignancies such as melanoma (Kamb et al, 1994), bladder cancer (Cairns et al, 1995) and renal cancer (Schraml et al, 2001).

Gain of 1q is a relatively frequent abnormality in ependymomas, and has been emphasised in CGH studies of paediatric tumours, where it has been reported in up to 22% of cases (Reardon et al, 1999).

Activating GNAS mutations are a frequent and characteristic genetic abnormality of LAMN.

Amplification of the proto-oncogene MET is a frequent (10 20%) molecular abnormality in gastric cancer (Kuniyasu et al, 1992; Nessling et al, 1998; Sakakura et al, 1999), and a MET-tyrosine kinase inhibitor (TKI) has been shown to induce apoptosis in gastric cancer cells with MET amplification (Smolen et al, 2006; Okamoto et al, 2010).

A frequent abnormality in human infants is spina bifida, in which the spine fails to close over and a gap is left in the vertebral column.

Thus, promoter methylation of DLEC1 is a frequent and tumour-specific epigenetic abnormality in CRC and gastric cancer.