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Additionally, IL-10 has been shown to be a feedback regulator of Th1, Th2, and allergenic immune responses [ 3, 4].
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Interestingly, Rpn4p is a feedback regulator of YAP1 and PDR1 [ 37].
In the scheme of RBC turnover, CO can be regarded as a "feedback" regulator by stimulating splenic erythropoiesis, which differs from the EPO-dependent process in the bone marrow.
This gene is an excellent candidate for such an effect because it is a feedback negative regulator of tumor necrosis factor signaling through nuclear factor-κB (NF-κB) [ 8- 10].
DUSP1 appears to be a major feedback regulator of the innate immune response, and to play a critical role in preventing septic shock and multi-organ dysfunction during pathogenic infection [36].
We have therefore proposed SP to be a positive feedback regulator of platelet activation.
Fibroblast growth factor 19 (FGF19) is proposed to be a negative feedback regulator of hepatic bile acid (BA) synthesis.
The problem addressed is to design a feedback regulator that can stabilize an equilibrium of the closed-loop system and, around this equilibrium, to synthesize a required dispersion of random states of the corresponding system.
This process is heavily regulated at the transcriptional level, principally by the transcriptional activator Sfp1p [ 55, 56], which is downstream to, and a feedback regulator of, the central growth-rate-regulating kinase TOR [ 72].
Nutlin-3 is a small molecule that binds MDM2, which is a negative feedback regulator of p53 activity by forming a complex with p53.
The mkp3 gene encodes a dual specificity phosphatase which was cloned as a member of fgf8 synexpression group and is a negative feedback regulator of FGF8 signaling.
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