Sentence examples for be a downstream target from inspiring English sources

For example, the multi-drug exporter channel protein ABCB1 was identified to be a downstream target of β-catenin in CML54.

Gli1 is known to be a downstream target of SHH signaling.

In fact, MYB appears to be a downstream target of c-Myc.

These results suggest that Erk2 may be a downstream target of cystatin C.

GSK3β is known to be a downstream target of HGF[27], [28], [29].

Fabp7 has also been shown to be a downstream target of Notch signaling pathways during CNS development [31].

Next, we examined the effect of Hes1 on expression of the c-myc gene, which is known to be a downstream target of Notch signaling [7], [8].

4E-binding protein 1 (4EBP1) is a downstream target of mTOR.

We wondered whether Ezh2 is a downstream target of JNK in regulating Bim expression.

Our findings show that Ezh2 is a downstream target of P38α/JNK pathways, establishing a connection between critical P38α/JNK signals and PRC2, an essential epigenetic regulator.

The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer.