Sentence examples for be a downstream member from inspiring English sources
These findings suggest that Ebp1 may be a downstream member of an ErbB-3-regulated signal transduction pathway.
Akt is a downstream member of the PI3K cascade, which plays an important role in cell growth, death, adhesion and migration and is frequently activated in cancer cells (Lin et al, 2003).
Rahman and colleagues showed that there is correlation between MEK1 amplification (a downstream member of EGFR pathway) and worse progression-free survival in ovarian carcinoma patients [ 24].
MAPK signalling pathway is a downstream target of Ras family members and activating KRAS mutations are one of the main features underlying CC development and resistance to therapy.
GADD45α is a downstream target of p53 and a member of a group of genes induced by DNA damaging agents and growth arrest signals.
And there's a downstream model since we'll be sending a lot of traffic.
Another Fos family member, c-Fos, is known to be a STAT3 downstream target gene as well.
These findings indicate that galectin-3 is a novel member of signaling proteins downstream of tyrosine kinase, and suggest that it plays roles in supporting repair or survival of the injured hepatocytes rather than their proliferation that is likely to be initiated later than 72 h.
In addition, Western blot and immunohistochemical analyses were performed on downstream members of the MAPK pathway in order to assess the contribution of each of these components.
