Sentence examples for be a downstream factor from inspiring English sources

Therefore, PhaPR1 could be a downstream factor in the PhaNPR1-mediated defense pathway.

Akt has been shown to be a downstream factor of SphK1, promoting cell proliferation and survival in several cancers such as leukemia, glioblastoma, and prostate cancer.

HMGB1 seems to be a downstream factor of apoptosis in the final common pathway to organ damage in severe sepsis as indicated by observations that prevention of lymphocyte apoptosis improved survival after CLP [ 23], whereas anti-HMGB1 treatment reduced lethality in the same model without influencing apoptosis [ 19].

Although we did not provide direct evidence to show that EAF1 is a downstream factor of non-canonical Wnt4 signaling, the possibility exists that this is the case based on the conserved structure and function between EAF1 and EAF2/U19.

At the same time, EAF2/U19 is a downstream factor in the non-canonical Wnt 4 signaling pathway required for eye development in Xenopus laevis, and along with EAF1, contributes to convergence and extension movements in zebrafish embryos through Wnt maintenance.

IGF2 is a downstream factor of IGF2BPs, especially IGF2BP2.

Being a downstream factor of mTOR, p70S6K is directly and only regulated by mTORC1.

PI3K is a downstream factor of IRS-1 and controls the phosphorylation of Akt.

We also showed that the AKT pathway was a downstream factor of SBSN.

Smad3 is a downstream factor of TGF- β/Activin/Nodal signaling.

NF-κB, which is a downstream factor of LOX-1, is a pivotal transcription factor involved in atherosclerosis.