Sentence examples for be a downstream component from inspiring English sources

Hes1 is known to be a downstream component of the Notch signaling pathway and a critical regulator of multiple stem cell populations in the developing embryo [22].

In the present investigation, we discovered an NAC domain-containing protein from soybean, GmNAC6 (Glycine max NAC6), to be a downstream component of the integrated pathway.

These data indicate that JIP1 is likely to be a downstream component of a c-Abl-dependent signaling pathway controlling axonal growth.

Differently from the full-length LOXL2, MAPK8 seems to be a downstream component of LOXL2 Δe13, as RNAi-mediated knockdown of MAPK8 results in cell migration blockage promoted by LOXL2 Δe13, but not by the full-length LOXL2 activity [ 123].

The presence of two binding sites for c-Rel, a subunit of NFκ-B, and the experimental data obtained with transgenic mice for c-Rel, suggest that LGALS4 could be a downstream component of the NFκ-B pathway, known to be involved in the regulation of tumorogenesis [ 44, 45].

We also showed that PhaPR1 is a downstream component of PhaNPR1-mediated SAR and have identified the promoter region in the PhaPR1 gene.

Signal transducer and activator of transcription-3 (STAT-3) is a downstream component of the Epidermal Growth Factor Receptor (EGFr) signaling process that may facilitate the resistance of tumor cells to conventional cancer treatments.

Stat3 is a downstream component of leukemia inhibitory factor (LIF) signaling, which is integral in maintaining ES cells in an undifferentiated state.

HWP1 is a downstream component of cAMP-PKA dependent pathway and is positively regulated by EFG1, but its expression is independent of the MAP kinase cascade, the second well-known pathway implicated in hyphae formation [11], [31].

Treatment of control cultures with the Rac1 inhibitor, NSC23376 reduced TH+ neurite length (39% +4%reduction), presumably due to antagonism of endogenous Wnt signaling as well as other potential axon guidance pathways for which Rac1 is a downstream component.

TCF7L1 is a downstream component of the Wnt signaling pathway.