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In this small study, there was a clear difference in response depending on HIV status, suggesting that EE with superimposed HIV enteropathy may be a distinct pathophysiological condition.
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Whether BA retention is a distinct pathophysiological entity or a biochemical epiphenomenon of severity of critical illness or even a compensatory mechanism with potential beneficial (e.g. metabolic or even anti-inflammatory) effects remains unclear [6].
Moreover, there is a distinct pathophysiological connection linking increased RAS activity and the metabolic alterations.
The reduced or absent response of villous architecture to our nutritional intervention in the presence of HIV suggests this is a distinct pathophysiological condition, where HIV infection alters the sequelae of EE.
This observation may be explained by a distinct pathophysiological process.
An "endotype" is proposed to be a subtype of a condition defined by a distinct pathophysiological mechanism.
ARD has enjoyed little recognition as a discrete clinical entity and this is due mainly to a lack of a distinct pathophysiological profile [ 4, 5].
It has been proposed that the CCR5-expressing glial cells could play a distinct pathophysiological role in contributing to the progression of injury and/or be a part of intrinsic repair mechanisms [62].
Conversely, the enhancement of these active motor phenomena during emotional stimulation suggests a relation with genuine cataplexy and thus a distinct pathophysiological role of hypocretinergic interactions.
There is controversy as to whether it is a distinct radiological and pathological entity or a pathophysiological change superimposed on a pre-existing lesion [2].
It is possible that there is a distinct subgroup with overlap of FD and IBS having a generalized rather than a regional disorder of gut with common pathophysiological mechanisms.
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CEO of Professional Science Editing for Scientists @ prosciediting.com