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Although some might think a snake would be a difficult target, it is not.
While the components pertussis toxin (PT) and filamentous hemagglutinin (FHA) have been successfully purified, the third component, pertactin, proves to be a difficult target due to its very low concentration.
Here we describe the generation and experimental validation of two different single-chain antibody variable fragment libraries that efficiently generate binders to peptides, a class of molecules that has proven to be a difficult target for antibody generation.
It is considered to be a difficult target for an amateur telescope.
The atypical Rio2 kinase, which possesses no significant sequence similarity to other protein kinases, would be a difficult target for standard approaches at homology modeling.
Although vaccines are important in preventing viral infections by inducing neutralizing antibodies (nAbs), HIV-1 has proven to be a difficult target and escapes humoral immunity through various mechanisms.
Similar(51)
It's a difficult target for internationally sourced cars and trucks to reach.
Yet such demands are a difficult target for even the most diligent governor (equivalent to a mayor).
The posterior insula-medial operculum is one of the earliest areas to process nociceptive information but is a difficult target.
Some upstate Democratic leaders began floating Kennedy's name as a prospective opponent to Keating, who was a difficult target for Democrats.
But Majerus had always been a difficult target because he makes roughly $1 million at Utah, and Texas Athletic Director DeLoss Dodds had said that the basketball coach wouldn't make more than the new football coach Mack Brown, who earns $750,000 annually.
More suggestions(16)
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be a tempting target
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Justyna Jupowicz-Kozak
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