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Not only may the discrimination of oncocytoma from RCC be challenging, but also the presence of oncocytoma with concurrent RCC may be a diagnostic problem.
Co-infections can be a diagnostic problem as one infection can easily undermine the existence of the other.
These prove to be a diagnostic problem but most fat-containing renal cell carcinomas also contain calcium[ 27 30], a feature that is rare in angiomyolipomas.
Evaluation of palpable neck masses may be a diagnostic problem in pediatric patients, with differential diagnosis including congenital, inflammatory, tumoral and traumatic lesions.
Since metastatic clear-cell RCC must be distinguished from a variety of neoplasms with clear-cell features including primitive tumors of thyroid, interpretation of FNAC may be a diagnostic problem for the pathologist [ 6, 7] and imposes the combination of routine immunohistochemical studies.
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As true epithelial cysts of the pancreas are extremely rare, these are a diagnostic problem.
These thyroid disturbances in the frame of non-thyroidal illness is a diagnostic problem which needs focused attention.
Considering that a diagnostic instrument is meant to be used in situations where there is a diagnostic problem, diagnostic research should be performed in relevant patient populations (the 'relevant domain') [ 40].
On the other hand, local involvement of vessels and surrounding organs is still a diagnostic problem.
Despite advances in diagnostic techniques such as imaging, esophagogastroduodenoscopy, magnetic resonance imaging and dual-phase spiral computer tomography, early diagnosis of gastric adenocarcinoma is still a diagnostic problem for clinicians.
The central idea in this framework is the recognition that the biased parameter identification problem can be viewed as a diagnostic problem, and methods from fault diagnosis literature may be brought in to improve the performance.
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