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Climate change, and our success or failure in dealing with it, will be a defining challenge.
Unfortunately, access to timely help is proving to be a defining challenge of the college mental health crisis.
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"This is a defining challenge of our future," he said.
This is a defining challenge for basic income schemes based on cryptocurrencies, and some have addressed it more convincingly than others.
Giving every child a fair chance in life is a defining challenge for our generation, and it must be tackled head-on.
Democratic nominee Hillary Clinton, on the other hand, said that the science on climate change "is crystal clear," and that it is a "defining challenge of our time".
In December 2013, Obama declared that growing income inequality is a "defining challenge of our time" and called on Congress to bolster the safety net and raise wages.
The interpretation of human genome variation is a defining challenge in human biology for the foreseeable future.
"Africa is poised for a defining challenge," he said.
Trust is a crucial part of a company's license to operate and is set to become a defining challenge of brand building.
In a way, my book was really continuing the lines of recent discussions, that is to say, we've identified the problem and we've seen some of the reasons for it, and we've seen our political leaders and our religious leaders all saying this is a serious problem — a "defining challenge of our time" to quote your president.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com