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While it remains possible that intracellular pH-induced changes to talin or other molecules may be a complementary mechanism of pH-induced integrin regulation, this does not exclude the possibility of direct extracellular pH-mediated integrin activation.
A significant correlation between SFRP-2 methylation and presence of JAK2V617F in our data supports the hypothesis that epigenetic dysregulation may be a complementary mechanism to genetic aberrations.
Thus, our results suggested that the loss of RASSF1A expression might be a complementary mechanism in the onset of colorectal cancer in addition to K-ras mutations.
According to our data, we speculated that loss of RASSF1A expression might be a complementary mechanism in the onset of colorectal cancer in addition to K-ras mutations.
Motivational interviewing, appeared to be a complementary mechanism for encouraging the goal setting process to occur and was often featured in existing self-management interventions [ 29].
Huang et al.[ 23] noticed that the lipoxygenase (LOX) gene family has been notably expanded in the cucumber genome and proposed that this might be a complementary mechanism to deal with biotic stresses.
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This response can be a complementary defense mechanism to the increased systemic antimicrobial peptide production following injury and infection.
Epigenetic disturbances are postulated to be a complementary or alternative mechanism to genetics [ 11, 12].
Epigenetics might be a complementary or alternative mechanism to the JAK2V617F mutation in the pathogenesis of Ph-MPN, leading to dysregulation of JAK-STAT signal transduction and thus to growth factor hypersensitivity.
This may be due to a complementary mechanism which compensates for the deletion of GATA2.
In zebrafish, genomic redundancy with mpv17-like paralogues was proposed as a complementary mechanism.
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