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The induction of PPAR γ-mediated programs might be a compensatory elevation of adipocyte differentiation against depleting fat.
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Our finding that mitochondrial oxidative phosphorylation stimulated by substrates other than fatty acids is also compromised, and that there is a compensatory elevation of complex IV activity, complex V expression and glycolysis further supports the idea that there is crosstalk between bioenergetic and metabolic pathways[31].
However, some studies have found elevated retinal NO in proliferative diabetic retinopathy [35], therefore ADMA elevation may actually be a compensatory mechanism to decrease pathologically elevated NO.
This elevation may be a compensatory mechanism that, in part, counteracts early insulin resistance.
Thus, elevation of plasma IL-10 could be a compensatory mechanism in FDR subjects in response to the attenuated low-grade inflammation after BR.
Conclusion: Fetal-placental vasodilation may be a compensatory mechanism to improve hypoxic conditions.
MnSOD deficiency has been shown to result in oxidative stress and heart failure (33), whereas a compensatory elevation in catalase levels has been observed in failing human hearts (34).
The unexpected inverse association may reflect a compensatory elevation of adipokine levels in response to early AD pathology, but it has also been inversely related to weight loss that often precedes the onset of clinical dementia.
In addition, the depletion of caspase-3 by siRNA induces a compensatory elevation in the caspase-7 level [38].
Suppression of one arm can lead to a compensatory elevation in the other [ 10, 12, 14].
This suggests that C. albicans has the natural ability to adapt to caspofungin treatment through a compensatory elevation of chitin content.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com