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There appears to be a common pathway toward death for malignant and nonmalignant diseases.
A soluble iron salt, namely, ferric nitrilotriacetate (FeNTA), can induce nephrotoxicity and kidney cancer in rats and mice models, suggesting that the activation of Wnt signalling may be a common pathway through which iron contributes to malignant progression (Torti and Torti, 2013).
Bone anabolic action of other hormones like parathyroid hormone, growth hormone, and thyroid hormone are reported to be mediated by IGF-I signaling [33] [36], and it is possible that the IGF-I/Akt1 pathway might be a common pathway for actions of these major hormones in bone.
PHOX seems to be a common pathway for these femtomolar-acting compounds.
mTOR and VEGF seem to be a common pathway in breast cancer and in hemECs, involving enhanced angiogenesis.
Endogenous changes in retinoid metabolism associated with increased retinoid accumulation, expression, and toxicity may be a common pathway for the development of many forms of cancer.
Similar(48)
One possibility is a common pathway of osmophobia and mood changes may provoke suicidality.
It has been reported that the oxidative stress is a common pathway for ZnO NP-induced oxidative damage [1, 50, 53].
Interruption of the blood supply of the femoral head is a common pathway.
The polyphagous larval endoparasitoid Meteorus pulchricornis (Wesmael, 1835) (Hymenoptera: Braconidae) also induces changes in the numbers of hemocytes of its host [35] indicating that this is a common pathway for host immune suppression in parasitoids.
This dysregulation is a common pathway system among four NFPA subtypes.
More suggestions(15)
be a dominant pathway
be a direct pathway
be a common theory
be a constructive pathway
be a common denominator
be a common practice
be a common problem
be a central pathway
be a common scoreline
be a viable pathway
be a unifying pathway
be a fundamental pathway
be a unique pathway
be a common goal
be a clinical pathway
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com