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Notably, other familial PD-linked gene products, parkin [61], DJ-1 [63], [63], and PINK1 [65], [65] are also associated with Akt signaling, supporting an intriguing notion that alterations in Akt signaling may be a common pathologic factor in PD.
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Degenerative disc disease is a common pathologic disorder accompanied by both structural and biochemical changes.
Degenerative spondylolisthesis is a common pathologic condition that leads to lumbar instability and significant clinical symptoms.
The excessive deposition of type I collagen is a common pathologic feature of all fibrotic diseases.
Our findings suggest that PNI is a common pathologic feature of ESCCs removed by radical esophagectomy.
Pleuropericardial involvement is a common pathologic finding in patients with Whipple's disease, but rarely causes clinical symptoms.
Remarkably, the mice receiving p185wt Abi1 shRNA cells did not develop splenomegaly, which is a common pathologic characteristic of Bcr-Abl-induced leukemogenesis.
Fibrotic reactions in the airways of the lung or the pulmonary interstitium are a common pathologic outcome after exposure to a wide variety of toxic agents, including metals, particles or fibers.
It is a common pathologic end-point for a number of processes, including damage by toxins, metabolic diseases, or virus-induced hepatitis, autoimmune hepatitis, passive congestion secondary to heart failure, or infection with parasites.
This increase in the ratio of the mRNA for non-α1/α1 subunits was present soon after pilocarpine-induced status epilepticus and also several months later, when the rats had developed spontaneous temporal lobe seizures, suggesting that the increased ratio in the non-α1/α1 subunits is a common pathologic mechanism that occurs following seizures, regardless of etiology and duration [ 14].
Low-grade epilepsy-associated tumors (LEAT) represent a common pathologic substrate in the setting of medically intractable chronic epilepsy.
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