Sentence examples for be a common mediator from inspiring English sources

While the ROS may be a common mediator responsible for the potent activity of the HCTs, the different characteristics of the small subunit proteins are probably associated with the subunit-selectivity of inhibition.

It was argued that nitric oxide (NO) may be a common mediator of GTN, histamine and CGRP-induced headache; otherwise, CGRP may be the common mediator of GTN, histamine and CGRP [45].   3.

For example, an endocrine factor might be a common mediator of progeny production and life span.

Our findings suggest that daily drug use may be a common mediator for a range of early risk factors [ 31].

Interestingly, several recent studies have revealed that Sirt1, one of seven mammalian sirtuin/Sir2 genes in the NAD+-dependent deacetylase family, could be a common mediator that explains the health benefits under calorie restriction [ 4, 5].

While hepatic steatosis associated with visceral adiposity may be a common mediator for elevated GGT and insulin resistance [ 19], GGT may be a marker of oxidative stress [ 20, 21].

Because Smad4 is a common mediator of the TGF-β signaling pathway, we next addressed the question of whether miR-146a affects the cellular responses to TGF-β.

These results suggest that 11 β -HSD1 activity in liver and adipose tissue is a common mediator of hypertension, hypertriglyceridemia, glucose intolerance, and insulin resistance in metabolic syndrome.

As a key mediator of fibrogenesis, transforming growth factor- β (TGF- β) plays a critical role in diabetic nephropathy, and Smad4 is a common mediator in TGF- β signaling [ 4– 6].

Ceriello et al. have demonstrated that there are independent and cumulative effects of postprandial hypertriglyceridemia and postprandial hyperglycemia on endothelial function and have pointed out that oxidative stress is a common mediator of both postprandial states [ 27].

Connective tissue growth factor is a common mediator of tissue fibrosis and can be activated by various stimulations, such as mechanical stretch, inflammation, hyperoxidative stress, enhanced activation of the renin angiotensin system, etc.