Axon degeneration is a common hallmark of many neurodegenerative diseases.
Fraga, M. F. et al. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.
Oxidative stress is a common hallmark of neuronal cell death associated with neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, as well as brain stroke/ischemia and traumatic brain injury.
Altered expression of microRNAs is a common hallmark of cancer that we demonstrate can be used to alter expression of a potent wild-type viral gene to achieve tumor-specific replication of an engineered vesicular stomatitis virus (VSV).
The brain accumulation of abnormal proteins is a common hallmark of multiple neurodegenerative diseases.
Genome-wide hypo-methylation, in combination with CGI specific hyper-methylation, is a common hallmark of cancer development [7].
The autoregulation of ECF-sigma factor expression is a common hallmark of this family of regulators, and has been observed amongst a great many of their number [34].
On the other hand, we determined whether the levels of certain candidate proteins were affected by the mutation since degradation is a common hallmark of Hsp90 clients upon Hsp90 inhibition.
Whether the phenomenon of major effector genes is a common hallmark of insect AMPs or not, further investigation needed to be done will be helpful in understanding the evolution of insect immune system.
