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However, the idiosyncratic liver toxicity observed with troglitazone does not appear to be a class effect.
The harm can be a class effect or uniquely associated with a particular class member.
18 Liver toxicity is considered to be a class effect of PI3K/Akt/mTOR pathway inhibitors.
Phosphodiesterase inhibitors, like catecholamines, have similar detrimental outcomes, and this appears to be a class effect [ 13, 14].
It remains to be ascertained whether this would be a class effect for all FGFR1 IIIc antibodies.
2, 3 Evidence from randomized clinical trials suggests that this may be a class effect of the renin-angiotensin system inhibitors.
Similar(37)
The new data about Bextra "renders the evidence that this is a class effect overwhelming," he argued.
While Novo claims the thyroid cancer issue is a class effect, there is no credible evidence to support this claim.
Further investigation are necessary to discover all the substrates involved in this process and to understand if this novel action of sildenafil is specific for this molecule or it is a class effect of PDE-5i.
Increased levels of circulating VEGF ligands are a class effect of anti-VEGF agents.
The study concludes that there is a class effect of SSRIs on heart defects.
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