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People still ask me this today and it continues to be a challenging question to answer.
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Optimal subject number is a challenging question for preclinical studies.
Roseman: So, it's a challenging question to answer, so the short answer is no.
With such a shift the ability of existing ventilation systems in meeting the new requirements is a challenging question for researchers.
In addition, the ability to tune dynamic range and kinetic rates of optogenetic actuators is a challenging question that is heavily explored with computational methods devised to facilitate optimization of these systems.
While numerous gene mutations can be identified from each cancer genome, what these mutations mean for cancer is a challenging question to address, especially for those from less understood putative new cancer genes.
It is a challenging question to estimate the spreading speeds of (1.1), of which the corresponding undelayed system with classical Laplacian diffusion were studied by Lin [45], Pan [46], Wang and Zhang [47], Wang and Zhao [48].
It is a challenging question; what do you get a great man who is so ill?
It's a challenging question to answer because each child and family is different.
To what extent these limits on the functional output imply similar tight limits on the properties of the neuronal circuits is a challenging question because it entails many technical and conceptual difficulties.
Whether this situation also applies to other CCN proteins is a challenging question.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com