Sentence examples for be a central modulator from inspiring English sources

Recently, SP1 was shown to be a central modulator of p53-induced apoptosis in humans [ 52].

The mammalian target of rapamycin (mTOR) pathway is widely regarded to be a central modulator of nutrient sensing and growth, which is known to adjust metabolism, increase autophagy, and reduce protein synthesis during CR (Johnson et al., 2013).

Within the past decade it became increasingly clear that the brain microvascular endothelium is a dynamic barrier, with p-glycoprotein being a central modulator of barrier function.

Since then it has been demonstrated that hepcidin is a central modulator of inflammation-associated anemia, not only by controlling the expression of ferroportin on intestinal cells and macrophages [ 5], but also via a direct inhibitory effect of hepcidin on erythropoiesis [ 6].

Hence, TRPV1 should be considered a central modulator of the self-maintenance of CNI.

We expect glial cells modulators to be a central theme in future drug development efforts.

Although these studies cited above have identified different modulators by which a cell/neuron alters mitochondrial membrane potential, they are in good agreement with our findings, whereby uncoupling mechanism proves to be a central regulator of cellular response to stress.

We speculate that the effects of yoga respiratory training on sympathovagal balance may be due to a central modulator regulatory effect.

The TGFβ co-receptor endoglin has been described as a central modulator of these signaling pathways in endothelial cells and chondrocytes [ 7, 8].

Synaptic trafficking is a key modulator of α-secretase activity.

A central modulator of EMT is Snail1, a potent transcriptional repressor of E-cadherin, the predominant cell cell adhesion molecule present on nearly all epithelial cell types 29.