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Since H3 Ser10 phosphorylation has been linked with both cell cycle and transcription control [7] [10], [20], [21], we reason this could be a biphasic effect, which on the one hand impacts the cell cycle, on the other hand, influences transcription.
There seems to be a biphasic effect of G-actin.
There seems to be a biphasic effect of G-actin? 6) Figure 6 figure supplement 1: why is there no effect of F585A and I589A?
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In females, however, there was a biphasic effect with increasing parathion dose (treatment, p < 0.0002).
One possibility is that there is a biphasic effect of female gonadal hormone deficiency, which may temporarily interfere in early implant-tissue integration and may be associated with a failure to upregulate a select set of bone extracellular matrix genes [ 9].
Carrageenan-induced inflammation is considered to be a biphasic model.
This could be attributed to a biphasic effect of vasopressin causing a strong initial vasoconstriction, with a consecutive vasodilatation [ 26, 27].
The exact function of leptin in OA is undetermined, although it is proposed to have a biphasic effect [ 22], with low levels facilitating cartilage synthesis, and excess leptin causing cartilage inflammation and degeneration [ 23].
Genistein is known to have a biphasic effect on tumor growth and metastasis, where low concentrations are stimulatory and high concentrations are inhibitory [ 21].
Obviously there are many possible variables that contribute to this, but one important thing to remember is that alcohol has a "biphasic" effect.
This is another example of a biphasic effect of NO, with beneficial effects at low doses and deleterious effects at high doses.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com