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Given the mechanism of action of these drugs in combination (i.e. enhanced G0/G1 arrest without enhanced apoptosis), an enhanced clinical benefit rate that includes an assessment of stable disease may be a better end-point for such randomized phase II trials, especially if FTIs ultimately contribute to prolonged control of the disease.
They argue that this is a better end user experience.
13, 20, 22 Perhaps with a larger-sized cohort, recurrence might be a better study end point.
In such instances, base deficit (or other global parameters of tissue perfusion) may be a better index for the end-point of resuscitation.
Giroud might be a better bet at this point.
"I'd think it would be a better story if he can keep playing to the point where he wants it to end".
"If she can play that way, I do not believe there's a better point guard in the country that can play both ends of the court".
CTCs may be a superior surrogate end point, as they are highly reproducible and correlate better with overall survival than do changes determined by traditional radiology [ 67, 68].
"It was a better 7-point lead," Coach Al Groh said.
Breast cancer is a coprimary end point.
The point is a unique end point for and.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com