There are also global interactions between pathways, such that activation of one pathway facilitates or attenuates the response of a battery of target genes of another pathway, in a coordinated manner.
To protect the cells from oncogenic insults, the transcription factor p53 acts as "the guardian of the genome" by regulating a battery of target genes involved in cell cycle arrest, apoptosis, senescence, and DNA repair.
As transcription factors, HOX proteins control a battery of target genes encoding cellular functions required for cell identity, cell growth and differentiation, as well as cell cell and cell matrix interactions [ 19- 22].
First, almost all FOG-1 targets (94%) were also FOG-3 targets, which is unlikely by chance (see Results) and suggests that FOG-1 and FOG-3 work together to regulate a battery of common targets.
Taken together, our analysis is consistent with the idea that the OMA proteins promote oogenesis in part through the translational regulation of a battery of mRNA targets that mediate myriad biochemical and reproductive functions.
This suite of K-Channels provides a battery of new targets for future research utilizing pharmacological and genetic techniques to manipulate brain nuclei, functional circuits, or even specific cell types.
The potential for toxicity of DvSnf7 RNA was evaluated with a harmonized battery of non-target organisms (NTOs) that included invertebrate predators, parasitoids, pollinators, soil biota as well as aquatic and terrestrial vertebrate species.
The lifespan of Caenorhabditis elegans is regulated by multiple signalling pathways that converge on a battery of downstream target genes.
The most likely mechanism contributing to this Nrf2-mediated protection against cancer development is the cell's ability to detoxify carcinogens and to combat mutagenic ROS via the activation of the battery of Nrf2-responsive targenesenes.
