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With the spiked AT batch the sensitivity of the assay was determined to detect at least a concentration of 0.06 IU heparin/ml AT.
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We present a methodology to evaluate the sensitivity of pharmaceutical batch processes to scaling up.
The AuNPs were poured on the silanized glass surface for 24 hours in humid environment to avoid the evaporation of the colloidal AuNPs solution from the surface and to ensure complete coverage to minimize variations in the sensitivity between different batches of the nanoparticles immobilized on the substrate.
Also, the sensitivity and specificity for the two batches were similar.
To check the sensitivity of the PAM, all cell batches were assayed in virus titrations using a PRRSV stock (LV) with a known virus titer.
The sensitivity and specificity of individual batches of antigen was also very similar, as was the sensitivity and specificity of the panel of antigens as a whole, demonstrating the robustness of an assay on the basis of a panel approach.
Furthermore, the batch effect correction implemented leads to a substantial increase in the sensitivity of statistical tests.
This factor can be used as a criterion in designing a process for sequential batch self-assembly, because the factor indicates the differences in the sensitivity.
The sensitivity and specificity of individual batches of antigen varied slightly between groups of patients; however, the sensitivity and specificity of the panel of antigens as a whole remained constant.
The sensitivity and selectivity of the procedure is firstly studied in batch.
However, the sensitivity function profiles are not symmetrical to those exhibited by regular batch columns.
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