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On this basis we propose that the subset of L. interrogans genes that have no orthologs in either L. biflexa or L. borgpetersenii may contain virulence factors that are responsible for the more severe form of leptospirosis.
On this basis, we propose that the primary determinant of E2F binding to the origin regions might not be primary DNA sequence recognition by E2F itself, but its interaction with chromatin-bound Rb, consistent with the information that chromatin-bound Rb is also detected during the S-phase [36].
On this basis, we propose that managing RE patients by using MSCs will be an attractive therapeutic approach in the future.
On this basis, we propose that substituting a RARα-selective or specific agonist for the RAR pan-agonist ATRA should improve the therapeutic response.
On that basis, we propose that PKD1L2 and defective fatty acid synthesis should be assessed, respectively, as a genetic risk factor and as a precipitating cause of neuromuscular disorders in humans.
On this basis, we propose that it should extra focus on the antibiotic usage and prescription practice introduction of MS in the medical curriculum, and at the same time strengthen the antibiotic knowledge education for MS and public.
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On this basis, we proposed that LSC responsible for MRD of CML home in vivo within severely hypoxic areas of bone marrow [3] where normal hematopoietic stem cells physiologically reside (the hypoxic stem cell niches) [4] [7].
On this basis, we proposed that MHC-determined resistance to Marek's disease could be due to the cell surface expression polymorphism of class I molecules (Kaufman et al., 1995; Kaufman and Salomonsen, 1997).
On that basis, we propose the general hypothesis that combination therapies consisting of at least one mitophagy inhibitor and one non-mitochondrial autophagy stimulator might be useful in the treatment of cancer.
On that basis, we propose quantification classification criteria for thoracic pedicles that could help surgeons predict whether a screw could be inserted into a thoracic pedicle during PVCR, thus guiding the instrumentation of thoracic pedicles with the free-hand technique.
On that basis, we propose an analytical process model of organizational capacity for continuous innovation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com