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To compare all estimators on a fair basis, we assumed that when the trial stopped at the first stage, an unconditional MLE was used.
On that basis we assumed that the population using peat was approximately half of the population that used solid fuel, i.e. the same as coal and wood together [ 22].
On this basis, we assumed that low amounts of soluble Aβ induce early pathological changes at cellular level that may precede the amyloidogenic cascade and one of these changes is the induction of the unfolded state of p53, suggesting a role of the protein in the early pathogenesis of AD [ 3].
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On a conservative basis, we assume that food purchased in restaurants (not including takeaway meals) will not change in price as a result of the tax (eating out in 2010 contributed only 11% of daily calorie intake).
On the basis of several studies, we assumed that identifying and managing women with GDM improved perinatal outcomes.
On the basis of these results, we assumed that patients with two or three risk factors could benefit from prophylaxis with TMP/SMX (sensitivity = 77.8%, specificity = 76.1%).
On the basis of previous studies, we assumed that the data were not missing at random and included a proxy variable for the missing group.
On the basis of household studies, we assumed that influenza disease would develop in 50% of patients infected with influenza virus (4 ).
On the basis of these findings, we assumed that CNP in CSF might have the role of a vasodilator in cerebral arteries.
On the basis of previous research, we assumed that 54% of the population at large would have positive skin test results and that SCIT would only be efficacious in 51% of the population.
Although the sulfur content of fuel oil can vary somewhat on a state-by-state basis, lacking detailed information, we assumed that a 0.5% sulfur content by weight was applicable nationally, as has been done previously [ 19].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com