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Close to 1,500 people living with HIV/AIDS are accompanied by the STD/AIDS Reference Center, on this basis, the sample size (n) was calculated by a Simple Random Sample, with a total of 177 patients, with a margin of error of 7% and a confidence level of 95%.
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13 When effect sizes were incompletely reported we contacted the corresponding author or estimated the SD on the basis of the sample size, median, and range, as suggested by Hozo and colleagues 26 or on the basis of the sample size and P value.
We used the following methods to calculate SDs when incompletely reported: (1) contact with the corresponding author or (2) estimation of the SD on the basis of the sample size, median and range as suggested by Hozo et al 22 or on the basis of the sample size and p value.
We used the following methods to compute effect sizes, when incompletely reported: contact with the corresponding author; estimation of the standard deviation (SD) on the basis of the sample size, median, and range as suggested by Hozo and colleagues [ 32] or on the basis of the sample size and P value; and imputation of the SD reported in similar studies.
The precision of the estimate for the difference in compliance between mono- and polytherapy treatment groups was used as the basis for the sample size calculation.
All trials were open label, and the basis for the sample size studied was provided in all studies.
In Australian general practice, we applied the CHF clinical indicators as the basis of the sample size calculations (estimated prevalence: 1%-4.1% for CHF vs. 10%-44% for HT) [ 50- 52].
On the basis of the sample size formula suggested for crossover trials (9) n = [(Z1−α/2 + Z1−β) × S]/2Δ, we determined that 21 patients were needed for adequate power.
H0: PgroupA = PgroupB vs. H1: PgroupA ≠ PgroupB.. Basis for the sample size considerations was the dichotomized endpoint in a parallel group design.
The primary outcome measure is adherence to treatment administration at home, and the range of the 95% confidence interval (CI) around this estimate was used as the basis for the sample size calculation.
Health-related QOL was among the prespecified secondary outcomes of the CaVenT study, while the primary outcome of PTS after 2 years was the basis for the sample size calculation.
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