Sentence examples for basis of tumor development from inspiring English sources

Given the high level in incidence rate and mortality rate of colon cancer, it would be important to better understand the biological basis of tumor development and progression, to develop markers for assessing onset or prediction of therapy outcome, as well as to identify targets for the development of novel therapies.

The cellular and molecular analyses of the DR4 mice provide substantial insight into the basis of tumor development.

The transcriptomic basis of tumor development and malignancy, however, remains largely unknown.

Human cancers modeled in Genetically Engineered Mouse Models (GEMMs) can provide important mechanistic insights into the molecular basis of tumor development and enable testing of new intervention strategies.

It is hoped that by identifying the common patterns of mutations underlying major cancer sub-types, we can better understand the molecular basis of tumor development and identify new diagnostics and therapeutic targets.

Clinical issue Glioblastomas (GBM) are the most common malignant brain tumors, and despite progress in elucidating the molecular and pathological basis of tumor development, current treatment strategies are largely ineffective.

The goal of understanding the molecular basis of human tumor development has been greatly facilitated by the use of animal model systems in which the etiology of tumor development can be carefully controlled.

Rubin H. Microenvironmental regulation of tumor development.

Cichowski K, Shih TS, Schmitt E, et al. Mouse models of tumor development in neurofibromatosis type 1. Science.

In summary, on the basis of a 5-year observation period, PTTG mRNA expression in the primary tumor improves the prediction of tumor recurrence especially in early stages of tumor development.

Understanding the molecular basis of skin tumor development has been greatly facilitated by the use of animal model systems in which tumor development can be carefully controlled [ 11].