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The 3-mm rule was not introduced on the basis of trial data, but on the basis of unsubstantiated, unpublished work.
On the basis of trial data, duloxetine would be the preferred SNRI and pregabalin would be the preferred α-2-δ agonist.
From a clinical standpoint, they demonstrated that linezolid had better efficacy than vancomycin for the treatment of MRSA NP (on the basis of trial data specifically in MRSA-confirmed patients), with fewer patients requiring a switch to second-line therapy.
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These calculations could be influenced by the introduction of a biosimilar IV trastuzumab, but this is not expected to occur in New Zealand until at least the first half of 2019 (on the basis of clinical trial data timelines on clinicaltrials.gov and estimated regulatory review processes).
The optimal duration of therapy with raloxifene, as with the other therapies, is still unclear, although at least 5 year treatment may be suggested and it is probably effective on the basis of clinical trial data in the prevention and treatment of postmenopausal osteoporosis.
The optimal duration of therapy with BPs is still unknown but since they are retained over time in the skeleton and may exert long-term effects, a 5 7 year course is probably safe and effective on the basis of clinical trial data.
The above-described analyses were all performed on the basis of trial-averaged data.
On the basis of clinical trials data and collective clinical experience, the American Diabetes Association/European Association for the Study of Diabetes and American Association of Clinical Endocrinologists have issued sets of recommendations for initiating and adjusting therapy for type 2 diabetes (28, 29).
However, the difficulty of accessing long-term human brain data after TBI constrains current studies of DOC, which are mostly treated on the basis of "trial" and "error".
On the basis of two years selection trial data a new and distinct elemicin rich strain of Cymbopogon khasianus was identified and named as Jor Lab L-10.
In guidelines for treatment, drugs and therapeutic procedures are evaluated on the basis of the published clinical trial data.
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