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A deeper comprehension of the biomineralization (BM) process is at the basis of tissue engineering and regenerative medicine developments.
Management is based on clinical experience, anecdotal evidence and the knowledge of the biological basis of tissue repair.
These design features should be based on a thorough understanding of the molecular and cellular basis of tissue regulation.
Experimental tools established over the past 100 years have been fundamental to start unraveling the cellular and molecular basis of tissue and limb regeneration.
The lack of icosahedral symmetry and modular organization in the genome of these viruses has facilitated engineering of viruses expressing fluorescent proteins, and these fluorescent proteins have provided important insights about the molecular and cellular basis of tissue tropism and pathogenesis.
Although the first records of this phenomenon date from the late 19th century, the mechanisms and molecular basis of tissue tropism are not fully understood.
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In this paper, the reference gene status of ribosomal protein genes was questioned by showing that as a group they were more highly expressed in tissues with faster cell division and by showing more profound differences between conditions on the basis of tissue-specific isoforms or transcript variants.
Candidate reference genes were selected from a total of 29 "housekeeping" genes that are often used for PCR normalization in other species [4], [7], [13], [14], [17], [18] or were predicted to be stably expressed in various Drosophila tissues on the basis of tissue-specific mRNA microarray data [9].
What is the molecular and biochemical basis of tissue-specific vulnerability to deoxythymidine phosphorylase deficiency?
Taken together, these results will help us to understand the molecular and regulatory basis of tissue-specific accumulation patterns of medicinally active specialized metabolites in kalmegh and to develop molecular breeding strategies to improve their yields.
However, a fleshless berry mutant has been described recently that promises to be a useful tool towards understanding the molecular genetic basis of tissue-specificity within the context of berry development [ 18].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com