Sentence examples for basis of this pathway from inspiring English sources

In the past decades the molecular basis of this pathway and the regulatory mechanism have been comprehensively studied, yet a great deal of new evidence indicates that cytochrome c release from mitochondria does not always lead to irreversible cell death, and that caspase activation can also have non-death functions.

A number of cell-based and biochemical studies have now provided strong evidence that TPC proteins mediate responses to NAADP and act as Ca2+-release channels from endolysosomal stores, although the precise mechanistic basis of this pathway remains to be fully described [ 14].

According to a simplified model, we deduced the carbon pore size equation that is expected to direct the synthesis of OMCs with tunable pore sizes on the basis of this synthesis pathway.

The molecular basis of this putative pathway remains to be clarified.

Although the molecular and biochemical basis of this metabolic pathway has been elusive yet, both glucose usage as well as lactate production are clinically relevant.

To take this into account, subjects' data were analyzed on the basis of the pathway they had followed in the Natural condition (whether optimal or not).

These results are in agreement with a previous report (Carroll et al., 2010) and highlight the essential role of CENP-C as the basis of the pathway of kinetochore assembly of the HIKM and CENP-T/W complexes.

This resulted in the creation of the ancestral eumetazoan repertoire of four Smads, forming the basis of the pathway in the Placozoa, the Cnidaria, the Arthropoda, and in the Lophotrochozoa.

Sensitive patients can then be further classified on the basis of the pathway responsible for everolimus efficacy (for example, the PI3K-dependent 'classic' pathway or the LKB1/AMPK metabolic pathway).

In particular, we have included: "These results are in agreement with a previous report (Carroll et al., 2010) and highlight the essential role of CENP-C as the basis of the pathway of kinetochore assembly of the HIKM and CENP-T/W complexes".

Additionally, subtype-specific molecular pathways and the genetic basis of these pathways have been characterised (Klatte and Pantuck, 2008).