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On the basis of this exploratory analysis, we have postulated further hypotheses about local spread and investigated them here.
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On the basis of the exploratory data from study 1, a second phase II study (study 9) was designed to determine whether repeated administration of lanicemine over 3 weeks at an interval of three infusions per week would consolidate and extend the therapeutic benefits observed from a single administration.
On the basis of results of this exploratory investigation we raise concerns that in countries like Finland, where BCG vaccination was routinely used, HBHA utility might not be sufficient for diagnostics because of inability to explicitly discriminate tuberculosis infection from immunoreactivity caused by previous BCG vaccination.
On the basis of an exploratory analysis, patients treated with sDC were at a 62% increased risk of disease progression compared to those treated with cDC (hazard ratio = 1.62; 95% CI, 1.08-2.45; P =.02).
Inclusion and exclusion criteria were established on the basis of an exploratory search of the literature.
The topic list was constructed on the basis of an exploratory meeting with key persons from the orthodox Protestant community, the NIP and CHCs who were represented in the advisory committee of the project.
Since PT1 was formulated essentially on the basis of initial exploratory research, we aimed at refining it through the in-depth study of one primary health care team before testing it in 4 other cases.
On the basis of an exploratory analysis of the Affymetrix gene expression profiling data, three genes, all located on chromosome 7, were identified for independent assessment of mRNA transcript levels using quantitative RT PCR (qRT PCR): EGFR, phosphoserine phosphatase (PSPH) and Rap guanine nucleotide exchange factor 5 (RAPGEF5).
We have attempted to overcome some of these limitations by using a polychoric correlation matrix as the basis of our exploratory analysis, and parallel analysis to determine significant eigenvalues, but have otherwise used the procedures available in SPSS which would be widely available.
The Commission and Member States will decide whether to prepare an EU electoral observation mission on the basis of an exploratory mission that will be sent in May 2003.
The results of this exploratory study represent the basis of specific predictions in future investigations on the effects of atomoxetine in Parkinson's disease and support the hypothesis that targeting noradrenergic dysfunction may represent a new parallel avenue of therapy in some of the cognitive and behavioural deficits seen in the disorder.
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