Sentence examples for basis of this defect from inspiring English sources

The embryological basis of this defect is shown in Fig. 10.

To determine the cell biological basis of this defect, we investigated the epithelia that will produce denticles.

However, the molecular basis of this defect is unknown.

The subtle differences that have been uncovered between Sar1A and Sar1B in these studies might also provide an explanation for the molecular basis of the defect in CMRD.

The above data suggest that abnormal cytokine secretion is not the basis of the defect in the T-dependent antibody response.

Although we cannot precisely map the basis of the defect in VAND in the present cross, future backcross studies could be used to identify factors required for efficient transmission in the cat.

The familial and molecular basis of the defect in both species is poorly understood although a previous description of the pattern of inheritance in a canine model in the Newfoundland dog breed suggested either an autosomal dominant with incomplete penetrance or a polygenic mode of inheritance (Pyle and Patterson 1976).

DOI: http://dx.doi.org/10.7554/eLife.11785.012 To define the molecular basis of the defect in interaction between EBOV and EhNPC1, we generated a panel of NPC1 domain C chimeras comprising sequences from permissive RaNPC1 and nonpermissive EhNPC1, and tested them in the GP-binding ELISA.

The approach taken by our laboratory group to answer these questions utilizes biochemistry and genetics; genetics to isolate mutants that have particular defects in development and biochemistry to determine the molecular basis of the defects.

To investigate the molecular basis of the defects, we examined the mRNA levels of selected genes associated with synthesis (tpsA, tpsC and orlA) or breakdown (treA and treB) of trehalose [21] [24, Christophe d'Enfert, personal communication].

Congenital heart defects are frequently observed in infants of diabetic mothers, but the molecular basis of the defects remains obscure.