Sentence examples for basis of the variant from inspiring English sources

A key issue to be resolved is the cellular basis of the variant response to WT p53 activation.

We investigated the variants detected in our analysis for their effects on basis of the variant annotation and effect prediction tool SNPEff [ 13] and their distribution across breed and non-breed horses.

On the basis of the variant frequency in each of the six management units from which more than 10 individuals were sampled, the expected heterozygosity (He) ranged from 0.33 to 0.85 (mean He, 0.65) (Table 4).

However, it has been difficult to calculate reliable PRSs in the clinic for complex disease on the basis of the variants identified by GWAS.

Comparative analysis of all 165 carriers, stratified on the basis of the Hb variant, showed that the α2/α1 average Hb variant percentage ranged from 0.98 to 1.67.

Studying the genetic basis of these variants may also shed light on evolution of the CUBN gene locus with respect to human evolutionary history.

The dendrograms obtained by MDR technique clearly showed complex and hierarchic pattern of interactions between ADE genes constituting the polygenic basis of the pathogenetic variants of asthma.

On the basis of the allelic variants characterized, we conclude that a number of these are plausible candidates for regulatory or structural mutations which may influence transcription or enzymatic activity of OAS1 and RNase L proteins.

Molecular mass MRP variants identified by Western blotting were in agreement with those expected on the basis of the mrp gene variant identified by PCR.

Ptrend was for genetic dose response by coding genotypes as 0, 1, and 2 on the basis of the number of variant alleles.

This phenomenon has been interpreted on the basis of variant selection of the Burgers orientation relationship commonly adopted between the α and β phases in these alloys.