Sentence examples for basis of the substrate from inspiring English sources

More recently, in order to get insight into the molecular basis of the substrate specificity of CpMan5B, a glycoside hydrolase (GH) family 5 enzyme exhibiting both β-1,4-mannosidic and β-1,4-glucosidic cleavage activities, Oyama et al. (2013) solved the crystal structure of the protein.

The molecular basis of the substrate and inhibitor specificity of factor Xa, the serine proteinase of the prothrombinase complex, was investigated by constructing two mutants of human antithrombin (HAT) in which the reactive site loop of the serpin from the P4 P4′ site was replaced with the corresponding residues of the two factor Xa cleavage sites in prothrombin (HAT/Proth-1 and HAT/Proth-2).

To investigate the peptide substrate specificity for Hsp40 Ydj1, we tried to synthesize different peptides designed on the basis of the substrate GWLYEIS (Table 2).

In the oxo/oxyl mechanism proposed on the basis of the substrate water-exchange results, redox tautomerism in the S1, S2, and S3 states is suggested to play an important role for the fast water-exchange rate.

Given that the substrate is specifically designed on the basis of the natural substrate, substrate and stereoselectivity is ensured due to nearly identical steric properties.

Within the SLC13 family, two groups of transporters may be differentiated on the basis of the substrates transported: NaS1 and NaS2 convey sulphate, while NaC1-3 transport carboxylates.

This structural feature forms the basis for the substrate specificity of DIS3L2 (Faehnle et al., 2014).

This study also provides the structural basis for the substrate specificity of cN-II, where Arg202, Asp206, and Phe157 seem to be important residues for purine/pyrimidine selectivity.

The structural basis for the substrate specificity of Ure2p enzymatic activity is an interesting problem that is fundamental to understanding the in vivo roles of Ure2p and its relationship to the GST structural family.

Our results define the molecular basis for the substrate specificity of a DEAD-box protein.

Also in the oblique deposition configurations, notable differences in the nanoscale morphology of the Pd films grown in the same conditions are observed on the basis of the supporting substrate.