Moreover, the difference in carbohydrate composition appears to be the basis of the decreased functional activity of the neonatal plasminogen.
To quantify the assembly properties of Cp149ox and define the basis of the decreased level of assembly, we determined the thermodynamics of Cp149ox assembly under equilibrium conditions.
The above-mentioned immune defects, occurring downstream of IL-15 deficiency, might be at the basis of the decreased immunosurveillance of mammary carcinomas.
To further dissect the basis of the decreased accumulation of [C]6-MP equivalents in K562-imatinib cells, separate efflux experiments were performed.
The weaker binding compared to that of WT for the majority of the N-terminal residues is expected on the basis of the decreased helix propensity of the A30P variant, as WT binds lipids in an α-helical mode.
In dermal fibroblasts, where the HAS-2 is the predominant isoform, glucocorticoids inhibit HAS mRNA almost completely, suggesting a molecular basis of the decreased HA in atrophic skin as a result of local treatment with glucocorticoids.
To understand the basis of the decreased size of CnB1-, NFand- aNFAT2-silencedced tumors, tumors were analyzed 5 or 15 days after orthotopic engraftment for proliferation and apoptosis by Ki67 and cleaved caspase 3 immunohistochemical staining, respectively.
Although epidemiological data can be used to better understand the endometriosis, further studies should investigate the genetics, environmental and physiopathological basis of the decreased BMI in women with endometriosis.
In order to examine the basis for the decreased number of Treg cells in the target organs of autoimmunity in CCR7−/− mice, Treg cells in lymphoid organs between WT and CCR7−/− mice were compared using flow cytomtric analysis.
