Sentence examples for basis of the binding from inspiring English sources

Similarly, the in-silico docking and molecular dynamics simulation clearly explain the theoretical basis of the binding mechanism of PAR with HSA.

On the basis of the binding pattern of 57, a novel scaffold can be proposed as a candidate of PDE inhibitors.

We develop a reusable ratiometric electrochemical biosensor on the basis of the binding of methylene blue (MB) to DNA with alternating AT base sequence for sensitive detection of adenosine.

In order to further enhance the anti-Aspergillus efficacy of our previously discovered antifungal lead compounds (I), two series of novel azoles featuring thieno[2,3-c]pyrrolidone and thieno[3,2-c]pyrrolidone nuclei were designed and evaluated for their in vitro activity on the basis of the binding mode of albaconazole using molecular docking, along with SARs of antifungal triazoles.

Molecular docking was then applied to locate the binding orientations and conformations of DHDMBF analogues with COX-2 and 5-LOX, respectively, leading to highly predictive CoMFA models constructed on the basis of the binding conformations with q2 values of 0.782 and 0.634 for COX-2 and 5-LOX, respectively.

To this end, we first mapped the structural basis of the binding of CD146 to canonical Wnt to domains 4 -5 of CD146 (Fig. 1K).

To rationalize the structural basis for the binding of LILRA3 to HLAIs, we attempted to characterize the structure of LILRA3 in the HLA-binding region.

It serves as the basis for the binding of further kinetochore proteins during mitosis.

Jia, Z., DeLuca, C. I., Chao, H. & Davies, P. L. Structural basis for the binding of a globular antifreeze protein to ice.

Here, we provide the thermodynamic and structural basis for the binding of this motif by the Src SH2 domain.

Finally, the molecular basis for the binding affinity of the peptides for the Fc fragment of hIgG was elucidated by molecular dynamics simulations.