Sentence examples for basis of substrate recognition from inspiring English sources

These results offer insights into the molecular basis of substrate recognition for the BmaI1 enzyme.

The structural basis of substrate recognition is mainly determined by post-translational modification of short epitopes (degrons) of the substrate, e.g. phosphorylation, hydroxylation or glycosylation [ 28].

The R2TP cochaperone complex plays a critical role in the assembly of multisubunit machines, including small nucleolar ribonucleoproteins (snoRNPs), RNA polymerase II, and the mTORC1 and SMG1 kinase complexes, but the molecular basis of substrate recognition remains unclear.

The goal was to characterise the sequence and structure of CALA in comparison to other α/β hydrolases despite its low sequence similarity and to understand the molecular basis of substrate recognition.

[26] Further insights into the structural basis of substrate recognition require the determination of the crystal structures of the DtcycA and DtcycB enzymes complexed with their substrates and Mg2+ ions.

Our studies provide a basis for structural and biochemical studies required for further understanding of substrate recognition and specificity.

A molecular understanding of substrate recognition of protein kinases provides an important basis for the development of substrate competitive inhibitors.

Figure 5 Schematic model of substrate recognition site of PahZ1KP-2.

Mechanisms of substrate recognition by calpain are altogether poorly understood, compared to other types of proteases.

F-box proteins are in charge of substrate recognition.

Adenosine has also been a major determinant of substrate recognition in some ribozymes selected to act on adenine-containing substrates.